Discontinuing antiplatelet therapy prior to surgery
Exposure to antiplatelet therapy often delays surgical procedures to avoid bleeding risks. Delays in surgical procedures and discontinuing a patient’s antiplatelet therapy impact the cost of care and increase the opportunity for a devastating ischemic event.
However, studies show that individuals vary widely in their response to antiplatelet medications.1
Measuring your patient’s response to their antiplatelet medications can help you optimize scheduling and creates the potential for:
- A shorter length-of-stay waiting for medications to wear off.
- Significant cost-savings as a result of reduced hospitalization.
- A shorter pre-op event window, making adverse events less likely.
Restoring Inhibition Prior to Discharge
Aspirin and sometimes clopidogrel are vital components to ensuring graft patency. However, just as there is variation in patients’ residual response when discontinuing antiplatelet medications, there is variation in response when resuming them. For that reason, the VerifyNow System can also be used prior to discharge to provide assurance that patients are responding to these medications as anticipated.
Assessing response to antiplatelet therapy should be easy.
it is.
Backed by numerous peer-reviewed studies that demonstrate clinical utility and analytical performance, the VerifyNow System provides you with an easy and rapid solution to help you assess your patient’s response to the following antiplatelet medications:
Click here to learn why you should join the growing number of surgeons who utilize the VerifyNow System for pre-surgical and post-surgical assessment to improve their patient care.
- Dupont, AG. et al. Antiplatelet therapies and the role of antiplatelet resistance in acute coronary syndrome. Thromb Res. 2009 May;124(1):6-13.
- Hochholzer, W. et al. Time Dependence of Platelet Inhibition After a 600-mg Loading Dose of Clopidogrel in a Large, Unselected Cohort of Candidates for Percutaneous Coronary Intervention. Circulation. 2005;111:2560-2564
- Price, MJ. et al. Onset and Offset of Platelet Inhibition After High-Dose Clopidogrel Loading and Standard Daily Therapy Measured by a Point-of-Care Assay in Healthy Volunteers. Am J Cardiol 2006;98:681–684
- Poston, RS. et al. Endothelial injury and acquired aspirin resistance as promoters of regional thrombin formation and early vein graft failure after coronary artery bypass grafting. J Thorac Cardiovasc Surg 2006;131:122-30
